Jan 7 JDN 2460318

There exists, right now, an extremely powerful antidepressant which is extremely cheap and has minimal side effects.

It’s so safe that it has no known lethal dose, and—unlike SSRIs—it is not known to trigger suicide. It is shockingly effective: it works in a matter of hours—not weeks like a typical SSRI—and even a single moderate dose can have benefits lasting months. It isn’t patented, because it comes from a natural source. That natural source is so easy to grow, you can do it by yourself at home for less than $100.

Why in the world aren’t we all using it?

I’ll tell you why: This wonder drug is called psilocybin. It is a Schedule I narcotic, which means that simply possessing it is a federal crime in the United States. Carrying it across the border is a felony.

It is also illegal in most other countries, including the UK, Australia, Belgium, Finland, Denmark, Sweden, Norway (#ScandinaviaIsNotAlwaysBetter), France, Germany, Hungary, Ireland, Japan, the list goes on….

Actually, it’s faster to list the places it’s not illegal: Austria, the Bahamas, Brazil, the British Virgin Islands, Jamaica, Nepal, the Netherlands, and Samoa. That’s it for true legalization, though it’s also decriminalized or unenforced in some other countries.

The best known antidepressant lies unused, because we made it illegal.

Similar stories hold for other amazingly beneficial drugs:

LSD also has powerful antidepressant effects with minimal side effects, and is likewise so ludicrously safe that we are not aware of a single fatal overdose ever happening in any human being. And it’s also Schedule I banned.

Ahayuasca is the same story: A great antidepressant, very safe, minimal side effects—and highly illegal.

There is also no evidence that psilocybin, LSD, or ahayuasca are addictive; and far from promoting the sort of violent, anti-social behavior that alcohol does, they actually seem to make people more compassionate.

This is pure speculation, but I think we should try psilocybin as a possible treatment for psychopathy. And if that works, maybe having a psilocybin trip should be a prerequisite for eligibility for any major elected office. (I often find it a bit silly how the biggest fans of psychedelics talk about the drugs radically changing the world, bringing peace and prosperity through a shift in consciousness; but if psilocybin could make all the world’s leaders more compassionate, that might actually have that kind of impact.)

Ketamine and MDMA at least do have some overdose risk and major side effects, and are genuinely addictive—but it’s not really clear that they’re any worse than SSRIs, and they certainly aren’t any worse than alcohol.

Alcohol may actually be the most widely-used antidepressant, and yet is clearly utterly ineffective; in fact, alcoholics consistently show depression increasing over time. Alcohol has a fatal dose so low it’s a common accident; it is also implicated in violent behavior, including half of all rapes—and in the majority of those rape cases, all consumption of alcohol was voluntary.

Yet alcohol can be bought over-the-counter at any grocery store.

The good news is that this is starting to change.

Recent changes in the law have allowed the use of psychedelic drugs in medical research—which is part of how we now know just how shockingly effective they are at treating depression.

Some jurisdictions in the US—notably, the whole state of Colorado—have decriminalized psilocybin, and Oregon has made it outright legal. Yet even this situation is precarious; just as has occurred with cannabis legalization, it’s still difficult to run a business selling psilocybin even in Oregon, because banks don’t want to deal with a business that sells something which is federally illegal.

Fortunately, this, too, is starting to change: A bill passed the US Senate a few months ago that would legalize banking to cannabis businesses in states where it is legal, and President Biden recently pardoned everyone in federal prison for simple cannabis possession. Now, why can’t we just make cannabis legal!?

The War on Drugs hasn’t just been a disaster for all the thousands of people needlessly imprisoned.

(Of course they had it the worst, and we should set them all free immediately—preferably with some form of restitution.)

The War of Drugs has also been a disaster for all the people who couldn’t get the treatment they needed, because we made that medicine illegal.

And for what? What are we even trying to accomplish here?

Prohibition was a failure—and a disaster of its own—but I can at least understand why it was done. When a drug kills nearly a hundred thousand people a year and is implicated in half of all rapes, that seems like a pretty damn good reason to want that drug gone. The question there becomes how we can best reduce alcohol use without the awful consequences that Prohibition caused—and so far, really high taxes seem to be the best method, and they absolutely do reduce crime.

But where was the disaster caused by cannabis, psilocybin, or ahayuasca? These drugs are made by plants and fungi; like alcohol, they have been used by humans for thousands of years. Where are the overdoses? Where is the crime? Psychedelics have none of these problems.

Honestly, it’s kind of amazing that these drugs aren’t more associated with organized crime than they are.

When alcohol was banned, it seemed to immediately trigger a huge expansion of the Mafia, as only they were willing and able to provide for the enormous demand of this highly addictive neurotoxin. But psilocybin has been illegal for decades, and yet there’s no sign of organized crime having anything to do with it. In fact, psilocybin use is associated with lower rates of arrest—which actually makes sense to me, because like I said, it makes you more compassionate.

That’s how idiotic and ridiculous our drug laws are:

We made a drug that causes crime legal, and we made a drug that prevents crime illegal.

Note that this also destroys any conspiracy theory suggesting that the government wants to keep us all docile and obedient: psilocybin is way better at making people docile than alcohol. No, this isn’t the product of some evil conspiracy.

Hanlon’s Razor: Never attribute to malice what can be adequately explained by stupidity.

This isn’t malice; it’s just massive, global, utterly catastrophic stupidity.

I might attribute this to Puritanical American attitude toward pleasure (Pleasure is suspect, pleasure is dangerous), but I don’t think of Sweden as particularly Puritanical, and they also ban most psychedelics. I guess the most libertine countries—the Netherlands, Brazil—seem to be the ones that have legalized them; but it doesn’t really seem like one should have to be that libertine to want the world’s cheapest, safest, most effective antidepressants to be widely available. I have very mixed feelings about Amsterdam’s (in)famous red light district, but absolutely no hesitation in supporting their legalization of psilocybin truffles.

Honestly, I think patriarchy might be part of this. Alcohol is seen as a very masculine drug—maybe because it can make you angry and violent. Psychedelics seem more feminine; they make you sensitive, compassionate and loving.

Even the way that psychedelics make you feel more connected with your body is sort of feminine; we seem to have a common notion that men are their minds, but women are their bodies.

Here, try it. Someone has said, “I feel really insecure about my body.” Quick: What is that person’s gender? Now suppose someone has said, “I’m very proud of my mind.” What is that person’s gender?

(No, it’s not just because the former is insecure and the latter is proud—though we do also gender those emotions, and there’s statistical evidence that men are generally more confident, though that’s never been my experience of manhood. Try it with the emotions swapped and it still works, just not quite as well.)

I’m not suggesting that this makes sense. Both men and women are precisely as physical and mental as each other—we are all both, and that is a deep truth about our nature. But I know that my mind makes an automatic association between mind/body and male/female, and I suspect yours does as well, because we came from similar cultural norms. (This goes at least back to Classical Rome, where the animus, the rational soul, was masculine, while the anima, the emotional one, was feminine.)

That is, it may be that we banned psychedelics because they were girly. The men in charge were worried about us becoming soft and weak. The drug that’s tied to thousands of rapes and car collisions is manly. The drug that brings you peace, joy, and compassion is not.

Think about the things that the mainstream objected to about Hippies: Men with long hair and makeup, women wearing pants, bright colors, flowery patterns, kindness and peacemongering—all threats to the patriarchal order.

Whatever it is, we need to stop. Millions of people are suffering, and we could so easily help them; all we need to do is stop locking people up for taking medicine.